On 9 March 2021, the European Chemical Agency (ECHA) has launched a Public Consultation on 8 potential Substances of Very High Concern (SVHC). The proposed substances in the consultation are listed as below, the deadline for commenting is 23 April 2021.
| # | Substance Name | EC Number | CAS Number | Proposing Authority | Reason for Proposing |
| 1 | 1,4-dioxane | 204-661-8 | 123-91-1 | Germany |
Equivalent level of concern having probable serious effects on the environment (Article 57f) Equivalent level of concern having probable serious effects on human health (Article 57f) |
| 2 |
2,2-bis(bromomethyl)propane1,3-diol (BMP); 2,2-dimethylpropan-1-ol, tribromo derivative/3-bromo-2,2-bis(bromomethyl)-1-propanol (TBNPA); 2,3-dibromo-1-propanol (2,3-DBPA) |
221-967-7 253-057-0 202-480-9 |
3296-90-0 36483-57-5 1522-92-5 96-13-9 |
Norway | Carcinogenic (Article 57a) |
| 3 | 2-(4-tert-butylbenzyl)propionaldehyde and its individual stereoisomers | - | - | Sweden | Toxic for reproduction (Article 57c) |
| 4 | 4,4'-(1-methylpropylidene)bisphenol; (bisphenol B) | 201-025-1 | 77-40-7 | France | Endocrine disrupting properties (Article 57(f) - environment AND human health |
| 5 | Glutaral | 203-856-5 | 111-30-8 | Sweden | Respiratory sensitising properties (Article 57(f) - human health) |
| 6 | Medium-chain chlorinated paraffins (MCCP) [UVCB substances consisting of more than or equal to 80% linear chloroalkanes with carbon chain lengths within the range from C14 to C17] | - | - | ECHA |
PBT (Article 57d) vPvB (Article 57e) |
| 7 | Orthoboric acid, sodium salt | 237-560-2 | 13840-56-7 | Sweden | Toxic for reproduction (Article 57c) |
| 8 | Phenol, alkylation products (mainly in para position) with C12-rich branched or linear alkyl chains from oligomerisation, covering any individual isomers and/ or combinations thereof (PDDP) | - | - | Germany |
Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) – human health) Endocrine disrupting properties (Article 57(f) – environment) |
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